human OPCML Over-expression AAV

Name 
AAV-h-OPCML
Cat No 
AAV-217423
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human OPCML.

AAV-217423
AAV-h-OPCML

Ready-to-use AAV expressing Human OPCML (opioid binding protein/cell adhesion molecule like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IGLON1; OBCAM; OPCM
Description (Vector)
OPCML encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. OPCML has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
4978
Gene Name (Vector)
opioid binding protein/cell adhesion molecule like
Gene Symbol
OPCML
HGNC ID
HGNC:8143
ORF Size (aa)
1065
ORF Size (bp)
1065 bp
RefSeq ID
NM_002545
RefSeq Synonyms
NM_002545, NM_001319106, NM_001319105, NM_001319104, NM_001319103, NM_001012393, BC143946, BC143945, BC126251, BC117254, BC074773, BC074742,
Species
human
UniGene ID
Hs.4817

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.