human OAT Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-217312
Availability:
3-5 weeks
Name:
AAV-h-OAT
This is an AAV expressing Human OAT.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- OAT
- Gene Name
- ornithine aminotransferase
- Gene ID
- 4942
- Gene Synonyms
- GACR; HOGA; OATASE; OKT
- ORF Size
- 1320 bp
- RefSeq#
- BC016928
- Gene Description
- OAT encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.
- UniGene ID
- Hs.523332
- HGNC ID
- HGNC:8091
Related Products
Control Products
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