human NRP1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-217094
Availability:
3-5 weeks
Name:
AAV-h-NRP1
This is an AAV expressing Human NRP1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- NRP1
- Gene Name
- neuropilin 1
- Gene ID
- 8829
- Gene Synonyms
- BDCA4; CD304; NP1; NRP; VEGF165R
- ORF Size
- 1830 bp
- RefSeq#
- BC007737
- Gene Description
- NRP1 encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
- UniGene ID
- Hs.714624
- HGNC ID
- HGNC:8004
Related Products
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