human NRF1 Over-expression AAV

Name 
AAV-h-NRF1
Cat No 
AAV-217074
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NRF1.

AAV-217074
AAV-h-NRF1

Ready-to-use AAV expressing Human NRF1 (nuclear respiratory factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ALPHA-PAL
Description (Vector)
NRF1 encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
Gene ID
4899
Gene Name (Vector)
nuclear respiratory factor 1
Gene Symbol
NRF1
HGNC ID
HGNC:7996
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
RefSeq ID
NM_005011
RefSeq Synonyms
NM_005011, NM_001293164, NM_001293163, NM_001040110, BC016925,
Species
human
UniGene ID
Hs.654363

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.