human NRBF2 Over-expression AAV

Name
AAV-h-NRBF2

Cat No
AAV-217067

Availability
4-5 weeks

This is an AAV expressing Human NRBF2.

AAV-217067

AAV-h-NRBF2

Ready-to-use AAV expressing Human NRBF2 (nuclear receptor binding factor 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Comodulator of PPAR and RXR; comodulator of PPAR and RXR 1; comodulator of PPAR and RXR 2; COPR; COPR1; COPR2; NRBF-2; nuclear receptor-binding factor 2

Description (eCommerce)

NRBF2 (nuclear receptor binding factor-2) was originally identified in a yeast two-hybrid screen for factors that interact with the peroxisome proliferator-activated receptor alpha (PPARalpha). In a second study, NRBF2 was also identified in a screen of a keratinocyte cDNA library and named COPR (comodulator of PPAR and RXR). In this study, NRBF2 was proposed to function as a modulator of transcriptional activity that functions to decrease rather than completely repress nuclear-receptor mediated gene expression.

Gene ID

29982

Gene Name (eCommerce)

nuclear receptor binding factor 2

Gene Name (Vector)

nuclear receptor binding factor 2

Gene Symbol

NRBF2

HGNC ID

HGNC:19692

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

864

ORF Size (bp)

864 bp

Protein Name (eCommerce)

Nuclear receptor-binding factor 2

RefSeq ID

NM_030759

RefSeq Synonyms

NM_030759, NM_001282405, BC011707,

Research Areas

Gene Expression,Nuclear Receptor Coactivators,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,transcription_translation

Species

human

Target Sentence

NRBF2 (nuclear receptor binding factor-2) was originally identified in a yeast two-hybrid screen for factors that interact with the peroxisome proliferator-activated receptor alpha (PPARalpha). In a second study, NRBF2 was also identified in a screen of a keratinocyte cDNA library and named COPR (comodulator of PPAR and RXR). In this study, NRBF2 was proposed to function as a modulator of transcriptional activity that functions to decrease rather than completely repress nuclear-receptor mediated gene expression.

UniGene ID

Hs.449628

UniProt ID (eCommerce)

Q96F24

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.