human NR0B1 Over-expression AAV
This is an AAV expressing Human NR0B1.
AAV-217025
AAV-h-NR0B1
Ready-to-use AAV expressing Human NR0B1 (nuclear receptor subfamily 0 group B member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AHC; AHCH; AHX; DAX-1; DAX1; DSS; GTD; HHG; NROB1; SRXY2
Description (Vector)
NR0B1 encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
Gene ID
190
Gene Name (Vector)
nuclear receptor subfamily 0 group B member 1
Gene Symbol
NR0B1
HGNC ID
HGNC:7960
ORF Size (aa)
1413
ORF Size (bp)
1413 bp
RefSeq ID
NM_000475
RefSeq Synonyms
NM_000475, BC011564,
Species
human
UniGene ID
Hs.268490
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.