human NOS2 Over-expression AAV

Name 
AAV-h-NOS2
Cat No 
AAV-216904
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NOS2.

AAV-216904
AAV-h-NOS2

Ready-to-use AAV expressing Human NOS2 (nitric oxide synthase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hepatocyte NOS; HEP-NOS; inducible NO synthase; inducible NOS; INOS; nitric oxide synthase 2, inducible; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; NOS; NOS type II; NOS, type II; NOS2A; peptidyl-cysteine S-nitrosylase NOS2
Description (eCommerce)
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide synthase is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. [taken from NCBI Entrez Gene (Gene ID: 4843)].
Description (Vector)
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.
Gene ID
4843
Gene Name (eCommerce)
nitric oxide synthase 2
Gene Name (Vector)
nitric oxide synthase 2
Gene Symbol
NOS2
HGNC ID
HGNC:7873
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3462
ORF Size (bp)
3462 bp
Protein Name (eCommerce)
Nitric oxide synthase, inducible
RefSeq ID
NM_000625
RefSeq Synonyms
NM_000625, BC144126, BC130283,
Research Areas
Cancer,Cardiology,Cardiovascular,Cytoskeleton,Gene Expression,HIF-1 Signaling,Hypoxia,IFN Signaling,Immunology,Innate Immunity,Interleukin Signaling,Lung Cancer,Neurobiology,Prolactin Signaling,Signal Transduction
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide synthase is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. [taken from NCBI Entrez Gene (Gene ID: 4843)].
UniGene ID
Hs.709191
UniProt ID (eCommerce)
P35228

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.