human NOL8 Over-expression AAV

Name 
AAV-h-NOL8
Cat No 
AAV-216868
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NOL8.

AAV-216868
AAV-h-NOL8

Ready-to-use AAV expressing Human NOL8 (nucleolar protein 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA62C3.3; bA62C3.4; C9orf34; NOP132; nucleolar protein 8; nucleolar protein Nop132
Description (eCommerce)
Nucleolar protein 132 (NOP132) was identified as a protein that interacts with the G protein, RRAG A (RAG A)/GTR1p, a member of the Ras-like small G protein family. NOP132 has been shown to interact mainly with proteins involved in ribosome biogenesis such as DDX47. NOP132 may play a role in recruiting pre-RNA processing proteins to regions of rRNA transcription in the nucleus.
Description (Vector)
NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth (Sekiguchi et al., 2004 (PubMed 14660641)).(supplied by OMIM, Mar 2008)
Gene ID
55035
Gene Name (eCommerce)
nucleolar protein 8
Gene Name (Vector)
nucleolar protein 8
Gene Symbol
NOL8
HGNC ID
HGNC:23387
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3300
ORF Size (bp)
3300 bp
Protein Name (eCommerce)
Nucleolar protein 8
RefSeq ID
NM_017948
RefSeq Synonyms
NM_017948, NM_001330722, NM_001256394, BC146810,
Research Areas
Cell Cycle,DNA Replication,Replication,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Nucleolar protein 132 (NOP132) was identified as a protein that interacts with the G protein, RRAG A (RAG A)/GTR1p, a member of the Ras-like small G protein family. NOP132 has been shown to interact mainly with proteins involved in ribosome biogenesis such as DDX47. NOP132 may play a role in recruiting pre-RNA processing proteins to regions of rRNA transcription in the nucleus.
UniGene ID
Hs.442199
UniProt ID (eCommerce)
Q76FK4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.