human NOD1 Over-expression AAV

Name 
AAV-h-NOD1
Cat No 
AAV-216854
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NOD1.

AAV-216854
AAV-h-NOD1

Ready-to-use AAV expressing Human NOD1 (nucleotide binding oligomerization domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CARD4; CLR7.1; NLRC1
Description (Vector)
NOD1 encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.
Gene ID
10392
Gene Name (Vector)
nucleotide binding oligomerization domain containing 1
Gene Symbol
NOD1
HGNC ID
HGNC:16390
ORF Size (aa)
2862
ORF Size (bp)
2862 bp
RefSeq ID
NM_006092
RefSeq Synonyms
NM_006092, BC040339,
Species
human
UniGene ID
Hs.405153

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.