human NMT1 Over-expression AAV

Name 
AAV-h-NMT1
Cat No 
AAV-216836
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NMT1.

AAV-216836
AAV-h-NMT1

Ready-to-use AAV expressing Human NMT1 (N-myristoyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
alternative, short form NMT-S; glycylpeptide N-tetradecanoyltransferase 1; long form, NMT-L; myristoyl-CoA:protein N-myristoyltransferase 1; NMT; NMT 1; Peptide N-myristoyltransferase 1; type I N-myristoyltransferase
Description (eCommerce)
NMT1 adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P30419].
Description (Vector)
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 (PubMed 1570339)).(supplied by OMIM, Nov 2008)
Gene ID
4836
Gene Name (eCommerce)
N-myristoyltransferase 1
Gene Name (Vector)
N-myristoyltransferase 1
Gene Symbol
NMT1
HGNC ID
HGNC:7857
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1491
ORF Size (bp)
1491 bp
Protein Name (eCommerce)
Glycylpeptide N-tetradecanoyltransferase 1
RefSeq ID
NM_021079
RefSeq Synonyms
NM_021079, BC006569, BC006538,
Research Areas
Acyltransferase,Apoptosis,Cytoskeleton,Host-Virus Interactions,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,infectious_disease,neurobiology
Species
human
Target Sentence
NMT1 adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P30419].
UniGene ID
Hs.532790
UniProt ID (eCommerce)
P30419

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.