human NFKBIZ Over-expression AAV

Name 
AAV-h-NFKBIZ
Cat No 
AAV-216657
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NFKBIZ.

AAV-216657
AAV-h-NFKBIZ

Ready-to-use AAV expressing Human NFKBIZ (NFKB inhibitor zeta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IKBZ; INAP; MAIL
Description (Vector)
NFKBIZ is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
64332
Gene Name (Vector)
NFKB inhibitor zeta
Gene Symbol
NFKBIZ
HGNC ID
HGNC:29805
ORF Size (aa)
2157
ORF Size (bp)
2157 bp
RefSeq ID
NM_031419
RefSeq Synonyms
NM_031419, NM_001005474, BC060800,
Species
human
UniGene ID
Hs.319171

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.