human NFKB2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-216646
Availability:
3-5 weeks
Name:
AAV-h-NFKB2
This is an AAV expressing Human NFKB2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- NFKB2
- Gene Name
- nuclear factor kappa B subunit 2
- Gene ID
- 4791
- Gene Synonyms
- CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p49/p100; p52
- ORF Size
- 2700 bp
- RefSeq#
- BC002844
- Gene Description
- NFKB2 encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. NFKB2 encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.
- UniGene ID
- Hs.73090
- HGNC ID
- HGNC:7795
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