human NEU1 Over-expression AAV
This is an AAV expressing Human NEU1.
AAV-216597
AAV-h-NEU1
Ready-to-use AAV expressing Human NEU1 (neuraminidase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NANH; NEU; SIAL1
Description (Vector)
NEU1 is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.
Gene ID
4758
Gene Name (Vector)
neuraminidase 1
Gene Symbol
NEU1
HGNC ID
HGNC:7758
ORF Size (aa)
1248
ORF Size (bp)
1248 bp
RefSeq ID
NM_000434
RefSeq Synonyms
NM_000434, BC011900, BC000722,
Species
human
UniGene ID
Hs.520037
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.