human NEIL3 Over-expression AAV

Name 
AAV-h-NEIL3
Cat No 
AAV-216566
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NEIL3.

AAV-216566
AAV-h-NEIL3

Ready-to-use AAV expressing Human NEIL3 (nei like DNA glycosylase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FGP2; FPG2; hFPG2; hNEI3; NEI3; ZGRF3
Description (Vector)
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 (PubMed 12509226)).(supplied by OMIM, Mar 2008)
Gene ID
55247
Gene Name (Vector)
nei like DNA glycosylase 3
Gene Symbol
NEIL3
HGNC ID
HGNC:24573
ORF Size (aa)
1818
ORF Size (bp)
1818 bp
RefSeq ID
NM_018248
RefSeq Synonyms
NM_018248, BC025954,
Species
human
UniGene ID
Hs.405467

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.