human NEFM Over-expression AAV

Name 
AAV-h-NEFM
Cat No 
AAV-216561
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NEFM.

AAV-216561
AAV-h-NEFM

Ready-to-use AAV expressing Human NEFM (neurofilament, medium polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NEF3; NF-M; NFM
Description (Vector)
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
4741
Gene Name (Vector)
neurofilament, medium polypeptide
Gene Symbol
NEFM
HGNC ID
HGNC:7734
ORF Size (aa)
2751
ORF Size (bp)
2751 bp
RefSeq ID
NM_005382
RefSeq Synonyms
NM_005382, NM_001105541, BC096757,
Species
human
UniGene ID
Hs.615287

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.