human NEBL Over-expression AAV

Name 
AAV-h-NEBL
Cat No 
AAV-216540
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NEBL.

AAV-216540
AAV-h-NEBL

Ready-to-use AAV expressing Human NEBL (nebulette). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LASP2; LNEBL
Description (Vector)
NEBL encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.
Gene ID
10529
Gene Name (Vector)
nebulette
Gene Symbol
NEBL
HGNC ID
HGNC:16932
ORF Size (aa)
3045
ORF Size (bp)
3045 bp
RefSeq ID
NM_006393
RefSeq Synonyms
NM_213569, NM_006393, NM_001173484, BC110453, BC110452,
Species
human
UniGene ID
Hs.5025

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.