human MTNR1B Over-expression AAV

Name 
AAV-h-MTNR1B
Cat No 
AAV-216034
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MTNR1B.

AAV-216034
AAV-h-MTNR1B

Ready-to-use AAV expressing Human MTNR1B (melatonin receptor 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FGQTL2; MEL-1B-R; MT2
Description (Vector)
MTNR1B encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. MTNR1B product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Gene ID
4544
Gene Name (Vector)
melatonin receptor 1B
Gene Symbol
MTNR1B
HGNC ID
HGNC:7464
ORF Size (aa)
1089
ORF Size (bp)
1089 bp
RefSeq ID
NM_005959
RefSeq Synonyms
NM_005959, BC069163,
Species
human
UniGene ID
Hs.569039

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.