human MSX2 Over-expression AAV

Name
AAV-h-MSX2

Cat No
AAV-215942

Availability
4-5 weeks

This is an AAV expressing Human MSX2.

AAV-215942

AAV-h-MSX2

Ready-to-use AAV expressing Human MSX2 (msh homeobox 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CRS2; FPP; HOX8; MSH; PFM; PFM1

Description (Vector)

MSX2 encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.

Gene ID

4488

Gene Name (Vector)

msh homeobox 2

Gene Symbol

MSX2

HGNC ID

HGNC:7392

ORF Size (aa)

804

RefSeq ID

NM_002449

RefSeq Synonyms

NM_002449, BC015509,

Species

human

UniGene ID

Hs.89404

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.