human MPO Over-expression AAV

Name 
AAV-h-MPO
Cat No 
AAV-215716
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MPO.

AAV-215716
AAV-h-MPO

Ready-to-use AAV expressing Human MPO (myeloperoxidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.
Gene ID
4353
Gene Name (Vector)
myeloperoxidase
Gene Symbol
MPO
HGNC ID
HGNC:7218
ORF Size (aa)
2238
ORF Size (bp)
2238 bp
RefSeq ID
NM_000250
RefSeq Synonyms
NM_000250, BC130476,
Species
human
UniGene ID
Hs.458272

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.