human MOGS Over-expression AAV

Name 
AAV-h-MOGS
Cat No 
AAV-215641
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MOGS.

AAV-215641
AAV-h-MOGS

Ready-to-use AAV expressing Human MOGS (mannosyl-oligosaccharide glucosidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDG2B; CWH41; DER7; GCS1
Description (Vector)
MOGS encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
7841
Gene Name (Vector)
mannosyl-oligosaccharide glucosidase
Gene Symbol
MOGS
HGNC ID
HGNC:24862
ORF Size (aa)
2514
ORF Size (bp)
2514 bp
RefSeq ID
NM_006302
RefSeq Synonyms
NM_006302, NM_001146158, BC117252, BC117250, BC028337,
Species
human
UniGene ID
Hs.516119

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.