human MEF2D Over-expression AAV

Name
AAV-h-MEF2D

Cat No
AAV-215274

Availability
4-5 weeks

This is an AAV expressing Human MEF2D.

AAV-215274

AAV-h-MEF2D

Ready-to-use AAV expressing Human MEF2D (myocyte enhancer factor 2D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MADS box transcription enhancer factor 2, polypeptide D; myocyte-specific enhancer factor 2D

Description (eCommerce)

Myocyte-specific enhancer factor 2D (MEF2D) is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth-factor and stress-induced genes. MEF2D mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14814].

Gene ID

4209

Gene Name (eCommerce)

myocyte enhancer factor 2D

Gene Name (Vector)

myocyte enhancer factor 2D

Gene Symbol

MEF2D

HGNC ID

HGNC:6997

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1545

ORF Size (bp)

1545 bp

Protein Name (eCommerce)

Myocyte-specific enhancer factor 2D

RefSeq ID

NM_005920

RefSeq Synonyms

NM_005920, NM_001271629, BC054520, BC040949,

Research Areas

Apoptosis,B-cell Receptor Signaling,Cardiac Development,Cardiology,Cardiovascular,Immunology,MAPK Signaling,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,Neurogenesis,NFAT Signaling,RNA Binding,Signal Transduction,Transcription Factor/Regulator

Research Areas (Faceted)

cardiovascular,cell_biology,developmental_biology,immunology,metabolism,neurobiology,signal_transduction,transcription_translation

Species

human

Target Sentence

Myocyte-specific enhancer factor 2D (MEF2D) is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth-factor and stress-induced genes. MEF2D mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14814].

UniGene ID

Hs.314327

UniProt ID (eCommerce)

Q14814

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.