human MATK Over-expression AAV

Name 
AAV-h-MATK
Cat No 
AAV-215068
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MATK.

AAV-215068
AAV-h-MATK

Ready-to-use AAV expressing Human MATK (megakaryocyte-associated tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CHK; CTK; HHYLTK; HYL; HYLTK; Lsk
Description (Vector)
MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Gene ID
4145
Gene Name (Vector)
megakaryocyte-associated tyrosine kinase
Gene Symbol
MATK
HGNC ID
HGNC:6906
ORF Size (aa)
1524
ORF Size (bp)
1524 bp
RefSeq ID
NM_002378
RefSeq Synonyms
NM_139355, NM_139354, NM_002378, BC003109, BC000114,
Species
human
UniGene ID
Hs.631845

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.