human MASTL Over-expression AAV

Name 
AAV-h-MASTL
Cat No 
AAV-215061
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MASTL.

AAV-215061
AAV-h-MASTL

Ready-to-use AAV expressing Human MASTL (microtubule associated serine/threonine kinase like). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GREATWALL; greatwall kinase homolog; greatwall protein kinase; GW; GWL; hGWL; MAST-L; Microtubule-associated serine/threonine-protein kinase-like; serine/threonine-protein kinase greatwall; THC2
Description (eCommerce)
MASTL (microtubule-associated serine/threonine-protein kinase-like) is an uncharacterized putative serine/threonine kinase which may be involved in megakaryocyte development. Defects in MASTL are the cause of thrombocytopenia type 2 (THC2) a disease characterized by decreased circulating platelets and increased potential for bleeding.
Description (Vector)
MASTL encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.
Gene ID
84930
Gene Name (eCommerce)
microtubule associated serine/threonine kinase like
Gene Name (Vector)
microtubule associated serine/threonine kinase like
Gene Symbol
MASTL
HGNC ID
HGNC:19042
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2640
ORF Size (bp)
2640 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase greatwall
RefSeq ID
NM_032844
RefSeq Synonyms
NM_032844, NM_001320757, NM_001320756, NM_001172304, NM_001172303, BC009107,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,DNA Damage/Repair,Kinase/Phosphatase,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
MASTL (microtubule-associated serine/threonine-protein kinase-like) is an uncharacterized putative serine/threonine kinase which may be involved in megakaryocyte development. Defects in MASTL are the cause of thrombocytopenia type 2 (THC2) a disease characterized by decreased circulating platelets and increased potential for bleeding.
UniGene ID
Hs.276905
UniProt ID (eCommerce)
Q96GX5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.