human MARCH9 Over-expression AAV

Name
AAV-h-MARCH9

Cat No
AAV-215029

Availability
4-5 weeks

This is an AAV expressing Human MARCH9.

AAV-215029

AAV-h-MARCH9

Ready-to-use AAV expressing Human MARCH9 (membrane associated ring-CH-type finger 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MARCH-IX; RNF179

Description (Vector)

MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 (PubMed 14722266); Hoer et al., 2007 (PubMed 17174307)).(supplied by OMIM, Apr 2010)

Gene ID

92979

Gene Name (Vector)

membrane associated ring-CH-type finger 9

Gene Symbol

9-Mar

HGNC ID

HGNC:25139

ORF Size (aa)

1041

ORF Size (bp)

1041 bp

RefSeq ID

NM_138396

RefSeq Synonyms

NM_138396, BC036455, BC009489,

Species

human

UniGene ID

Hs.632709

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.