human MAP3K11 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-214924
Availability:
3-5 weeks
Name:
AAV-h-MAP3K11
This is an AAV expressing Human MAP3K11.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MAP3K11
- Gene Name
- mitogen-activated protein kinase kinase kinase 11
- Gene ID
- 4296
- Gene Synonyms
- MEKK11; MLK-3; MLK3; PTK1; SPRK
- ORF Size
- 2544 bp
- RefSeq#
- BC011263
- Gene Description
- MAP3K11 is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
- UniGene ID
- Hs.502872
- HGNC ID
- HGNC:6850
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