human MAN2A1 Over-expression AAV

Name 
AAV-h-MAN2A1
Cat No 
AAV-214878
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MAN2A1.

AAV-214878
AAV-h-MAN2A1

Ready-to-use AAV expressing Human MAN2A1 (mannosidase alpha class 2A member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AMan II; GOLIM7; MANA2; MANII
Description (Vector)
MAN2A1 encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.
Gene ID
4124
Gene Name (Vector)
mannosidase alpha class 2A member 1
Gene Symbol
MAN2A1
HGNC ID
HGNC:6824
ORF Size (aa)
3432
ORF Size (bp)
3432 bp
RefSeq ID
NM_002372
RefSeq Synonyms
NM_002372, BC142696, BC142656,
Species
human
UniGene ID
Hs.432822

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.