human M6PR Over-expression AAV

Name 
AAV-h-M6PR
Cat No 
AAV-214761
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human M6PR.

AAV-214761
AAV-h-M6PR

Ready-to-use AAV expressing Human M6PR (mannose-6-phosphate receptor, cation dependent). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD-M6PR; CD-MPR; MPR 46; MPR-46; MPR46; SMPR
Description (Vector)
M6PR encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.
Gene ID
4074
Gene Name (Vector)
mannose-6-phosphate receptor, cation dependent
Gene Symbol
M6PR
HGNC ID
HGNC:6752
ORF Size (aa)
834
ORF Size (bp)
834 bp
RefSeq ID
NM_002355
RefSeq Synonyms
NM_002355, NM_001207024, BC024206,
Species
human
UniGene ID
Hs.134084

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.