human LILRB2 Over-expression AAV
This is an AAV expressing Human LILRB2.
AAV-213934
AAV-h-LILRB2
Ready-to-use AAV expressing Human LILRB2 (leukocyte immunoglobulin like receptor B2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD85D; ILT-4; ILT4; LIR-2; LIR2; MIR-10; MIR10
Description (Vector)
LILRB2 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
10288
Gene Name (Vector)
leukocyte immunoglobulin like receptor B2
Gene Symbol
LILRB2
HGNC ID
HGNC:6606
ORF Size (aa)
1797
ORF Size (bp)
1797 bp
RefSeq ID
NM_005874
RefSeq Synonyms
NM_005874, NM_001278406, NM_001278405, NM_001278404, NM_001278403, NM_001080978, BC036827,
Species
human
UniGene ID
Hs.655652
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.