human LDOC1 Over-expression AAV

Name 
AAV-h-LDOC1
Cat No 
AAV-213806
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human LDOC1.

AAV-213806
AAV-h-LDOC1

Ready-to-use AAV expressing Human LDOC1 (leucine zipper down-regulated in cancer 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BCUR1; Mar7; Mart7
Description (Vector)
LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
Gene ID
23641
Gene Name (Vector)
leucine zipper down-regulated in cancer 1
Gene Symbol
LDOC1
HGNC ID
HGNC:6548
ORF Size (aa)
441
RefSeq ID
NM_012317
RefSeq Synonyms
NM_012317, BC003104,
Species
human
UniGene ID
Hs.45231

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.