human KYNU Over-expression AAV

Name 
AAV-h-KYNU
Cat No 
AAV-213620
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KYNU.

AAV-213620
AAV-h-KYNU

Ready-to-use AAV expressing Human KYNU (kynureninase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KYNUU
Description (Vector)
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants.
Gene ID
8942
Gene Name (Vector)
kynureninase
Gene Symbol
KYNU
HGNC ID
HGNC:6469
ORF Size (aa)
924
ORF Size (bp)
924 bp
RefSeq ID
NM_003937
RefSeq Synonyms
NM_003937, NM_001199241, NM_001032998, BC000879,
Species
human
UniGene ID
Hs.470126

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.