human KRT75 Over-expression AAV

Name 
AAV-h-KRT75
Cat No 
AAV-213449
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KRT75.

AAV-213449
AAV-h-KRT75

Ready-to-use AAV expressing Human KRT75 (keratin 75). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
K6HF; KB18; PFB
Description (Vector)
KRT75 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. KRT75 is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).
Gene ID
9119
Gene Name (Vector)
keratin 75
Gene Symbol
KRT75
HGNC ID
HGNC:24431
ORF Size (aa)
1656
ORF Size (bp)
1656 bp
RefSeq ID
NM_004693
RefSeq Synonyms
NM_004693, BC160175,
Species
human
UniGene ID
Hs.697046

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.