human KRT3 Over-expression AAV

Name
AAV-h-KRT3

Cat No
AAV-213407

Availability
4-5 weeks

Categories
AAV, Over-Expression

This is an AAV expressing Human KRT3.

AAV-213407

AAV-h-KRT3

Ready-to-use AAV expressing Human KRT3 (keratin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CK3; K3

Description (Vector)

KRT3 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene ID

3850

Gene Name (Vector)

keratin 3

Gene Symbol

KRT3

HGNC ID

HGNC:6440

ORF Size (aa)

1884

ORF Size (bp)

1884 bp

RefSeq ID

NM_057088

RefSeq Synonyms

NM_057088, BC172453, BC156125,

Species

human

UniGene ID

Hs.680652

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.