human KLK2 Over-expression AAV

Name 
AAV-h-KLK2
Cat No 
AAV-213290
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KLK2.

AAV-213290
AAV-h-KLK2

Ready-to-use AAV expressing Human KLK2 (kallikrein related peptidase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hGK-1; hK2; KLK2A2
Description (Vector)
KLK2 encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. KLK2 is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.
Gene ID
3817
Gene Name (Vector)
kallikrein related peptidase 2
Gene Symbol
KLK2
HGNC ID
HGNC:6363
ORF Size (aa)
786
ORF Size (bp)
786 bp
RefSeq ID
NM_005551
RefSeq Synonyms
NM_005551, NM_001256080, NM_001002231, BC005196,
Species
human
UniGene ID
Hs.515560

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.