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human KCNMB3 Over-expression AAV

Name 
AAV-h-KCNMB3
Cat No 
AAV-212762
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human KCNMB3.

AAV-212762
AAV-h-KCNMB3

Ready-to-use AAV expressing Human KCNMB3 (potassium calcium-activated channel subfamily M regulatory beta subunit 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BKBETA3; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMBL; SLO-BETA-3; SLOBETA3
Description (Vector)
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.
Gene ID
27094
Gene Name (Vector)
potassium calcium-activated channel subfamily M regulatory beta subunit 3
Gene Symbol
KCNMB3
HGNC ID
HGNC:6287
ORF Size (aa)
825
ORF Size (bp)
825 bp
RefSeq ID
NM_014407
RefSeq Synonyms
NM_171830, NM_171829, NM_171828, NM_014407, NM_001163677, BC152860,
Species
human
UniGene ID
Hs.591285

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.