human JAK3 Over-expression AAV

Name
AAV-h-JAK3

Cat No
AAV-212574

Availability
4-5 weeks

This is an AAV expressing Human JAK3.

AAV-212574

AAV-h-JAK3

Ready-to-use AAV expressing Human JAK3 (Janus kinase 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK

Description (Vector)

JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Gene ID

3718

Gene Name (Vector)

Janus kinase 3

Gene Symbol

JAK3

HGNC ID

HGNC:6193

ORF Size (aa)

1860

ORF Size (bp)

1860 bp

RefSeq ID

NM_000215

RefSeq Synonyms

NM_000215, BC028068,

Species

human

UniGene ID

Hs.515247

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.