human IRF4 Over-expression AAV

Name 
AAV-h-IRF4
Cat No 
AAV-212408
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IRF4.

AAV-212408
AAV-h-IRF4

Ready-to-use AAV expressing Human IRF4 (interferon regulatory factor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LSIRF; MUM1; NF-EM5; SHEP8
Description (Vector)
IRF4 belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Gene ID
3662
Gene Name (Vector)
interferon regulatory factor 4
Gene Symbol
IRF4
HGNC ID
HGNC:6119
ORF Size (aa)
1356
ORF Size (bp)
1356 bp
RefSeq ID
NM_002460
RefSeq Synonyms
NM_002460, NM_001195286, BC015752,
Species
human
UniGene ID
Hs.401013

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.