human IL3RA Over-expression AAV

Name
AAV-h-IL3RA

Cat No
AAV-212191

Availability
4-5 weeks

This is an AAV expressing Human IL3RA.

AAV-212191

AAV-h-IL3RA

Ready-to-use AAV expressing Human IL3RA (interleukin 3 receptor subunit alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD123; hIL-3Ra; IL3R; IL3RAY; IL3RX; IL3RY

Description (Vector)

IL3RA is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

Gene ID

3563

Gene Name (Vector)

interleukin 3 receptor subunit alpha

Gene Symbol

IL3RA

HGNC ID

HGNC:6012

ORF Size (aa)

1137

ORF Size (bp)

1137 bp

RefSeq ID

NM_002183

RefSeq Synonyms

NM_002183, NM_001267713, BC035407,

Species

human

UniGene ID

Hs.632790

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.