human IGF2BP1 Over-expression AAV

Name 
AAV-h-IGF2BP1
Cat No 
AAV-211918
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IGF2BP1.

AAV-211918
AAV-h-IGF2BP1

Ready-to-use AAV expressing Human IGF2BP1 (insulin like growth factor 2 mRNA binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
coding region determinant-binding protein; CRDBP; CRD-BP; IGF2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; IMP1; IMP-1; insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP; insulin-like growth factor 2 mRNA-binding protein 1; VICKZ family member 1; VICKZ1; ZBP1; ZBP-1; zipcode-binding protein 1
Description (eCommerce)
Insulin-like growth factor 2 mRNA binding protein 1 (IMP1) is a member of the insulin-like growth factor 2 mRNA-binding protein family. IMP1 contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation [taken from NCBI Entrez Gene (Gene ID: 10642)].
Description (Vector)
IGF2BP1 encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
10642
Gene Name (eCommerce)
insulin like growth factor 2 mRNA binding protein 1
Gene Name (Vector)
insulin like growth factor 2 mRNA binding protein 1
Gene Symbol
IGF2BP1
HGNC ID
HGNC:28866
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1734
ORF Size (bp)
1734 bp
Protein Name (eCommerce)
Insulin-like growth factor 2 mRNA-binding protein 1
RefSeq ID
NM_006546
RefSeq Synonyms
NM_006546, NM_001160423, BC156957, BC152770,
Research Areas
BDNF Signaling,Cancer,Gene Expression,Immunology,MicroRNAs in Cancer,mRNA Binding,mRNA transport,Neurobiology,RNA Binding,RNA Processing,RNA Transport,Translational Control
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Insulin-like growth factor 2 mRNA binding protein 1 (IMP1) is a member of the insulin-like growth factor 2 mRNA-binding protein family. IMP1 contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation [taken from NCBI Entrez Gene (Gene ID: 10642)].
UniGene ID
Hs.144936
UniProt ID (eCommerce)
Q9NZI8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.