human HTRA1 Over-expression AAV

Name
AAV-h-HTRA1

Cat No
AAV-211713

Availability
4-5 weeks

This is an AAV expressing Human HTRA1.

AAV-211713

AAV-h-HTRA1

Ready-to-use AAV expressing Human HTRA1 (HtrA serine peptidase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11

Description (Vector)

HTRA1 encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.

Gene ID

5654

Gene Name (Vector)

HtrA serine peptidase 1

Gene Symbol

HTRA1

HGNC ID

HGNC:9476

ORF Size (aa)

1443

ORF Size (bp)

1443 bp

RefSeq ID

NM_002775

RefSeq Synonyms

NM_002775, BC172536, BC156552,

Species

human

UniGene ID

Hs.501280

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.