human HSPE1 Over-expression AAV

Name 
AAV-h-HSPE1
Cat No 
AAV-211675
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HSPE1.

AAV-211675
AAV-h-HSPE1

Ready-to-use AAV expressing Human HSPE1 (heat shock protein family E (Hsp10) member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
10 kDa chaperonin; 10 kDa heat shock protein, mitochondrial; chaperonin 10; CPN10; early-pregnancy factor; EPF; epididymis secretory sperm binding protein; GROES; heat shock 10kD protein 1 (chaperonin 10); heat shock 10kDa protein 1; HSP10
Description (eCommerce)
HSPE1 is a eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. It binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61604].
Description (Vector)
HSPE1 encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. HSPE1 and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.
Gene ID
3336
Gene Name (eCommerce)
heat shock protein family E (Hsp10) member 1
Gene Name (Vector)
heat shock protein family E (Hsp10) member 1
Gene Symbol
HSPE1
HGNC ID
HGNC:5269
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
309
Protein Name (eCommerce)
10 kDa heat shock protein, mitochondrial
RefSeq ID
NM_002157
RefSeq Synonyms
NM_002157, BC023518,
Research Areas
EGFR Signaling,Mitochondrion,Protein Folding,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
HSPE1 is a eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. It binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61604].
UniGene ID
Hs.1197
UniProt ID (eCommerce)
P61604

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.