human HNRPLL Over-expression AAV

Name
AAV-h-HNRPLL

Cat No
AAV-211418

Availability
4-5 weeks

This is an AAV expressing Human HNRNPLL.

AAV-211418

AAV-h-HNRPLL

Ready-to-use AAV expressing Human HNRNPLL (heterogeneous nuclear ribonucleoprotein L like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HNRPLL; SRRF

Description (Vector)

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 (PubMed 18669861)).(supplied by OMIM, Aug 2008)

Gene ID

92906

Gene Name (Vector)

heterogeneous nuclear ribonucleoprotein L like

Gene Symbol

HNRNPLL

HGNC ID

HGNC:25127

ORF Size (aa)

828

ORF Size (bp)

828 bp

RefSeq ID

NM_138394

RefSeq Synonyms

NM_138394, NM_001142650, BC017480, BC008217,

Species

human

UniGene ID

Hs.445497

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.