human HERC5 Over-expression AAV

Name 
AAV-h-HERC5
Cat No 
AAV-210954
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HERC5.

AAV-210954
AAV-h-HERC5

Ready-to-use AAV expressing Human HERC5 (HECT and RLD domain containing E3 ubiquitin protein ligase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CEB1; CEBP1
Description (Vector)
HERC5 is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
Gene ID
51191
Gene Name (Vector)
HECT and RLD domain containing E3 ubiquitin protein ligase 5
Gene Symbol
HERC5
HGNC ID
HGNC:24368
ORF Size (aa)
3075
ORF Size (bp)
3075 bp
RefSeq ID
NM_016323
RefSeq Synonyms
NM_016323, BC140716,
Species
human
UniGene ID
Hs.26663

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.