human GYPC Over-expression AAV

Name 
AAV-h-GYPC
Cat No 
AAV-210708
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GYPC.

AAV-210708
AAV-h-GYPC

Ready-to-use AAV expressing Human GYPC (glycophorin C (Gerbich blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD236; CD236R; GE; GPC; GPD; GYPD; PAS-2; PAS-2'
Description (Vector)
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
Gene ID
2995
Gene Name (Vector)
glycophorin C (Gerbich blood group)
Gene Symbol
GYPC
HGNC ID
HGNC:4704
ORF Size (aa)
387
RefSeq ID
NM_002101
RefSeq Synonyms
NM_016815, NM_002101, NM_001256584, BC106051, BC104247, BC104246,
Species
human
UniGene ID
Hs.59138

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.