human GYPC Over-expression AAV

Name
AAV-h-GYPC

Cat No
AAV-210708

Availability
4-5 weeks

This is an AAV expressing Human GYPC.

AAV-210708

AAV-h-GYPC

Ready-to-use AAV expressing Human GYPC (glycophorin C (Gerbich blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD236; CD236R; GE; GPC; GPD; GYPD; PAS-2; PAS-2'

Description (Vector)

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

Gene ID

2995

Gene Name (Vector)

glycophorin C (Gerbich blood group)

Gene Symbol

GYPC

HGNC ID

HGNC:4704

ORF Size (aa)

387

RefSeq ID

NM_002101

RefSeq Synonyms

NM_016815, NM_002101, NM_001256584, BC106051, BC104247, BC104246,

Species

human

UniGene ID

Hs.59138

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.