human GTF3C4 Over-expression AAV

Name
AAV-h-GTF3C4

Cat No
AAV-210656

Availability
4-5 weeks

This is an AAV expressing Human GTF3C4.

AAV-210656

AAV-h-GTF3C4

Ready-to-use AAV expressing Human GTF3C4 (general transcription factor IIIC subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

general transcription factor 3C 4; general transcription factor 3C polypeptide 4; general transcription factor IIIC, polypeptide 4, 90kDa; KAT12; TF3C-delta; TFIII90; TFIIIC 90 kDa subunit; TFIIIC290; TFIIIC90; TFIIICDELTA; transcription factor IIIC 90 kDa subunit; transcription factor IIIC subunit delta

Description (eCommerce)

General transcription factor 3C polypeptide 4 (GTF3C4/TFIIIC90) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C4/TFIIIC90 is required for RNA polymerase III transcription and interacts with TFIIIC220, TFIIIC110, TFCIIIC63, TFIIIB90, and RPC39. GTF3C4/TFIIIC90 has been shown to possess acetyltransferase activity specific for histone H3.

Gene ID

9329

Gene Name (eCommerce)

general transcription factor IIIC subunit 4

Gene Name (Vector)

general transcription factor IIIC subunit 4

Gene Symbol

GTF3C4

HGNC ID

HGNC:4667

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2469

ORF Size (bp)

2469 bp

Protein Name (eCommerce)

General transcription factor 3C polypeptide 4

RefSeq ID

NM_012204

RefSeq Synonyms

NM_012204, BC112245, BC104755, BC094774,

Research Areas

Acyltransferase,Gene Expression,Histone Modification,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,transcription_translation

Species

human

Target Sentence

General transcription factor 3C polypeptide 4 (GTF3C4/TFIIIC90) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C4/TFIIIC90 is required for RNA polymerase III transcription and interacts with TFIIIC220, TFIIIC110, TFCIIIC63, TFIIIB90, and RPC39. GTF3C4/TFIIIC90 has been shown to possess acetyltransferase activity specific for histone H3.

UniGene ID

Hs.656646

UniProt ID (eCommerce)

Q9UKN8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.