human GTF2E2 Over-expression AAV

Name 
AAV-h-GTF2E2
Cat No 
AAV-210635
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GTF2E2.

AAV-210635
AAV-h-GTF2E2

Ready-to-use AAV expressing Human GTF2E2 (general transcription factor IIE subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FE; General transcription factor IIE subunit 2; general transcription factor IIE, polypeptide 2, beta 34kDa; TF2E2; TFIIE beta subunit; TFIIE-B; TFIIE-beta; transcription initiation factor IIE subunit beta; TTD6
Description (eCommerce)
GTF2E2 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P29084].
Gene ID
2961
Gene Name (eCommerce)
general transcription factor IIE subunit 2
Gene Name (Vector)
general transcription factor IIE subunit 2
Gene Symbol
GTF2E2
HGNC ID
HGNC:4651
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
876
ORF Size (bp)
876 bp
Protein Name (eCommerce)
Transcription initiation factor IIE subunit beta
RefSeq ID
NM_002095
RefSeq Synonyms
NM_002095, BC030572,
Research Areas
Cancer,Gene Expression,Host-Virus Interactions,Transcription Factor/Regulator,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cell_biology,infectious_disease,transcription_translation
Species
human
Target Sentence
GTF2E2 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P29084].
UniGene ID
Hs.77100
UniProt ID (eCommerce)
P29084

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.