human GSTA4 Over-expression AAV
This is an AAV expressing Human GSTA4.
AAV-210596
AAV-h-GSTA4
Ready-to-use AAV expressing Human GSTA4 (glutathione S-transferase alpha 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GSTA4-4; GTA4
Description (Vector)
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis.
Gene ID
2941
Gene Name (Vector)
glutathione S-transferase alpha 4
Gene Symbol
GSTA4
HGNC ID
HGNC:4629
ORF Size (aa)
390
RefSeq ID
NM_001512
RefSeq Synonyms
NM_001512, BC063439, BC015523,
Species
human
UniGene ID
Hs.485557
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.