human GOPC Over-expression AAV

Name 
AAV-h-GOPC
Cat No 
AAV-210175
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GOPC.

AAV-210175
AAV-h-GOPC

Ready-to-use AAV expressing Human GOPC (golgi associated PDZ and coiled-coil motif containing). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAL; CFTR-associated ligand; dJ94G16.2; dJ94G16.2 PIST; FIG; fused in glioblastoma; golgi-associated PDZ and coiled-coil motif containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; GOPC1; PDZ protein interacting specifically with TC10; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10; PIST
Description (eCommerce)
CFTR-associated ligand (CAL) plays a role in intracellular protein trafficking and degradation. Cal may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. CAL may also regulate the intracellular trafficking of the ADR1B receptor [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9HD26].
Description (Vector)
GOPC encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
57120
Gene Name (eCommerce)
golgi associated PDZ and coiled-coil motif containing
Gene Name (Vector)
golgi associated PDZ and coiled-coil motif containing
Gene Symbol
GOPC
HGNC ID
HGNC:17643
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
Protein Name (eCommerce)
Golgi-associated PDZ and coiled-coil motif-containing protein
RefSeq ID
NM_020399
RefSeq Synonyms
NM_020399, NM_001017408, BC009553,
Research Areas
Golgi Apparatus,Neurobiology,Synapse,Transport
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
CFTR-associated ligand (CAL) plays a role in intracellular protein trafficking and degradation. Cal may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. CAL may also regulate the intracellular trafficking of the ADR1B receptor [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9HD26].
UniGene ID
Hs.191539
UniProt ID (eCommerce)
Q9HD26

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.