human GJA8 Over-expression AAV

Name 
AAV-h-GJA8
Cat No 
AAV-209918
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GJA8.

AAV-209918
AAV-h-GJA8

Ready-to-use AAV expressing Human GJA8 (gap junction protein alpha 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAE; CAE1; CTRCT1; CX50; CZP1; MP70
Description (Vector)
GJA8 encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
Gene ID
2703
Gene Name (Vector)
gap junction protein alpha 8
Gene Symbol
GJA8
HGNC ID
HGNC:4281
ORF Size (aa)
1299
ORF Size (bp)
1299 bp
RefSeq ID
NM_005267
RefSeq Synonyms
NM_005267, BC146507, BC140363,
Species
human
UniGene ID
Hs.632441

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.