human GIMAP5 Over-expression AAV

Name
AAV-h-GIMAP5

Cat No
AAV-209881

Availability
4-5 weeks

This is an AAV expressing Human GIMAP5.

AAV-209881

AAV-h-GIMAP5

Ready-to-use AAV expressing Human GIMAP5 (GTPase, IMAP family member 5). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HIMAP3; IAN-5; IAN4; IAN4L1; IAN5; IMAP3; IROD

Description (Vector)

GIMAP5 encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. GIMAP5 encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

Gene ID

55340

Gene Name (Vector)

GTPase, IMAP family member 5

Gene Symbol

GIMAP5

HGNC ID

HGNC:18005

ORF Size (aa)

924

ORF Size (bp)

924 bp

RefSeq ID

NM_018384

RefSeq Synonyms

NM_018384, BC011732,

Species

human

UniGene ID

Hs.647079

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.