human GGA1 Over-expression AAV

Name 
AAV-h-GGA1
Cat No 
AAV-209837
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GGA1.

AAV-209837
AAV-h-GGA1

Ready-to-use AAV expressing Human GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADP-ribosylation factor binding protein 1; ADP-ribosylation factor-binding protein GGA1; gamma-adaptin related protein 1; Gamma-adaptin-related protein 1; golgi-localized, gamma ear-containing, ARF-binding protein 1
Description (eCommerce)
Gamma-adaptin-related protein 1 (GGA1) is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins [taken from NCBI Entrez Gene (Gene ID: 26088)].
Description (Vector)
GGA1 encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
26088
Gene Name (eCommerce)
golgi associated, gamma adaptin ear containing, ARF binding protein 1
Gene Name (Vector)
golgi associated, gamma adaptin ear containing, ARF binding protein 1
Gene Symbol
GGA1
HGNC ID
HGNC:17842
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1659
ORF Size (bp)
1659 bp
Protein Name (eCommerce)
ADP-ribosylation factor-binding protein GGA1
RefSeq ID
NM_001001560
RefSeq Synonyms
NM_013365, NM_001172688, NM_001172687, NM_001001561, NM_001001560, BC044629,
Research Areas
Golgi Apparatus,Lysosome
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Gamma-adaptin-related protein 1 (GGA1) is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins [taken from NCBI Entrez Gene (Gene ID: 26088)].
UniGene ID
Hs.499158
UniProt ID (eCommerce)
Q9UJY5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.